The genome sequence of the SARS-associated coronavirus
Identifieur interne : 006369 ( Main/Exploration ); précédent : 006368; suivant : 006370The genome sequence of the SARS-associated coronavirus
Auteurs : Marco A. Marra [Canada] ; Steven J. M. Jones [Canada] ; Caroline R. Astell [Canada] ; Robert A. Holt [Canada] ; Angela Brooks-Wilson [Canada] ; Yaron S. N. Butterfield [Canada] ; Jaswinder Khattra [Canada] ; Jennifer K. Asano [Canada] ; Sarah A. Barber [Canada] ; Susanna Y. Chan [Canada] ; Alison Cloutier [Canada] ; Shaun M. Coughlin [Canada] ; Doug Freeman [Canada] ; Noreen Girn [Canada] ; Obi L. Griffith [Canada] ; Stephen R. Leach [Canada] ; Michael Mayo [Canada] ; Helen Mcdonald [Canada] ; Stephen B. Montgomery [Canada] ; Pawan K. Pandoh [Canada] ; Anca S. Petrescu [Canada] ; A. Gordon Robertson [Canada] ; Jacqueline E. Schein [Canada] ; Asim Siddiqui [Canada] ; Duane E. Smailus [Canada] ; Jeff M. Stott [Canada] ; George S. Yang [Canada] ; Francis Plummer [Canada] ; Anton Andonov [Canada] ; Harvey Artsob [Canada] ; Nathalie Bastien [Canada] ; Kathy Bernard [Canada] ; Timothy F. Booth [Canada] ; Donnie Bowness [Canada] ; Martin Czub [Canada] ; Michael Drebot [Canada] ; Lisa Fernando [Canada] ; Ramon Flick [Canada] ; Michael Garbutt [Canada] ; Michael Gray [Canada] ; Allen Grolla [Canada] ; Steven Jones [Canada] ; Heinz Feldmann [Canada] ; Adrienne Meyers [Canada] ; Amin Kabani [Canada] ; YAN LI [Canada] ; Susan Normand [Canada] ; Ute Stroher [Canada] ; Graham A. Tipples [Canada] ; Shaun Tyler [Canada] ; Robert Vogrig [Canada] ; Diane Ward [Canada] ; Brynn Watson [Canada] ; Robert C. Brunham [Canada] ; Mel Krajden [Canada] ; Martin Petric [Canada] ; Danuta M. Skowronski [Canada] ; Chris Upton [Canada] ; Rachel L. Roper [Canada]Source :
- Science : (Washington, D.C.) [ 0036-8075 ] ; 2003.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
We sequenced the 29,751-base genome of the severe acute respiratory syndrome (SARS)-associated coronavirus known as the Tor2 isolate. The genome sequence reveals that this coronavirus is only moderately related to other known coronaviruses, including two human coronaviruses, HCoV-OC43 and HCoV-229E. Phylogenetic analysis of the predicted viral proteins indicates that the virus does not closely resemble any of the three previously known groups of coronaviruses. The genome sequence will aid in the diagnosis of SARS virus infection in humans and potential animal hosts (using polymerase chain reaction and immunological tests), in the development of antivirals (including neutralizing antibodies), and in the identification of putative epitopes for vaccine development.
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 000978
- to stream PascalFrancis, to step Curation: 000013
- to stream PascalFrancis, to step Checkpoint: 000928
- to stream Main, to step Merge: 006877
- to stream Main, to step Curation: 006369
Le document en format XML
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Chan</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Cloutier, Alison" sort="Cloutier, Alison" uniqKey="Cloutier A" first="Alison" last="Cloutier">Alison Cloutier</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Coughlin, Shaun M" sort="Coughlin, Shaun M" uniqKey="Coughlin S" first="Shaun M." last="Coughlin">Shaun M. Coughlin</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Freeman, Doug" sort="Freeman, Doug" uniqKey="Freeman D" first="Doug" last="Freeman">Doug Freeman</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Girn, Noreen" sort="Girn, Noreen" uniqKey="Girn N" first="Noreen" last="Girn">Noreen Girn</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Griffith, Obi L" sort="Griffith, Obi L" uniqKey="Griffith O" first="Obi L." last="Griffith">Obi L. Griffith</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Leach, Stephen R" sort="Leach, Stephen R" uniqKey="Leach S" first="Stephen R." last="Leach">Stephen R. Leach</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Mayo, Michael" sort="Mayo, Michael" uniqKey="Mayo M" first="Michael" last="Mayo">Michael Mayo</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Mcdonald, Helen" sort="Mcdonald, Helen" uniqKey="Mcdonald H" first="Helen" last="Mcdonald">Helen Mcdonald</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Montgomery, Stephen B" sort="Montgomery, Stephen B" uniqKey="Montgomery S" first="Stephen B." last="Montgomery">Stephen B. Montgomery</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Pandoh, Pawan K" sort="Pandoh, Pawan K" uniqKey="Pandoh P" first="Pawan K." last="Pandoh">Pawan K. Pandoh</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Petrescu, Anca S" sort="Petrescu, Anca S" uniqKey="Petrescu A" first="Anca S." last="Petrescu">Anca S. Petrescu</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>24 aut.</sZ><sZ>25 aut.</sZ><sZ>26 aut.</sZ><sZ>27 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Robertson, A Gordon" sort="Robertson, A Gordon" uniqKey="Robertson A" first="A. Gordon" last="Robertson">A. Gordon Robertson</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>24 aut.</sZ><sZ>25 aut.</sZ><sZ>26 aut.</sZ><sZ>27 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Schein, Jacqueline E" sort="Schein, Jacqueline E" uniqKey="Schein J" first="Jacqueline E." last="Schein">Jacqueline E. Schein</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>24 aut.</sZ><sZ>25 aut.</sZ><sZ>26 aut.</sZ><sZ>27 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Siddiqui, Asim" sort="Siddiqui, Asim" uniqKey="Siddiqui A" first="Asim" last="Siddiqui">Asim Siddiqui</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>24 aut.</sZ><sZ>25 aut.</sZ><sZ>26 aut.</sZ><sZ>27 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Smailus, Duane E" sort="Smailus, Duane E" uniqKey="Smailus D" first="Duane E." last="Smailus">Duane E. Smailus</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>24 aut.</sZ><sZ>25 aut.</sZ><sZ>26 aut.</sZ><sZ>27 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Stott, Jeff M" sort="Stott, Jeff M" uniqKey="Stott J" first="Jeff M." last="Stott">Jeff M. Stott</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>24 aut.</sZ><sZ>25 aut.</sZ><sZ>26 aut.</sZ><sZ>27 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Yang, George S" sort="Yang, George S" uniqKey="Yang G" first="George S." last="Yang">George S. Yang</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>24 aut.</sZ><sZ>25 aut.</sZ><sZ>26 aut.</sZ><sZ>27 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Plummer, Francis" sort="Plummer, Francis" uniqKey="Plummer F" first="Francis" last="Plummer">Francis Plummer</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 aut.</sZ><sZ>35 aut.</sZ><sZ>36 aut.</sZ><sZ>37 aut.</sZ><sZ>38 aut.</sZ><sZ>39 aut.</sZ><sZ>40 aut.</sZ><sZ>41 aut.</sZ><sZ>42 aut.</sZ><sZ>43 aut.</sZ><sZ>44 aut.</sZ><sZ>45 aut.</sZ><sZ>46 aut.</sZ><sZ>47 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Andonov, Anton" sort="Andonov, Anton" uniqKey="Andonov A" first="Anton" last="Andonov">Anton Andonov</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 aut.</sZ><sZ>35 aut.</sZ><sZ>36 aut.</sZ><sZ>37 aut.</sZ><sZ>38 aut.</sZ><sZ>39 aut.</sZ><sZ>40 aut.</sZ><sZ>41 aut.</sZ><sZ>42 aut.</sZ><sZ>43 aut.</sZ><sZ>44 aut.</sZ><sZ>45 aut.</sZ><sZ>46 aut.</sZ><sZ>47 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Artsob, Harvey" sort="Artsob, Harvey" uniqKey="Artsob H" first="Harvey" last="Artsob">Harvey Artsob</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 aut.</sZ><sZ>35 aut.</sZ><sZ>36 aut.</sZ><sZ>37 aut.</sZ><sZ>38 aut.</sZ><sZ>39 aut.</sZ><sZ>40 aut.</sZ><sZ>41 aut.</sZ><sZ>42 aut.</sZ><sZ>43 aut.</sZ><sZ>44 aut.</sZ><sZ>45 aut.</sZ><sZ>46 aut.</sZ><sZ>47 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Bastien, Nathalie" sort="Bastien, Nathalie" uniqKey="Bastien N" first="Nathalie" last="Bastien">Nathalie Bastien</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 aut.</sZ><sZ>35 aut.</sZ><sZ>36 aut.</sZ><sZ>37 aut.</sZ><sZ>38 aut.</sZ><sZ>39 aut.</sZ><sZ>40 aut.</sZ><sZ>41 aut.</sZ><sZ>42 aut.</sZ><sZ>43 aut.</sZ><sZ>44 aut.</sZ><sZ>45 aut.</sZ><sZ>46 aut.</sZ><sZ>47 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Bernard, Kathy" sort="Bernard, Kathy" uniqKey="Bernard K" first="Kathy" last="Bernard">Kathy Bernard</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 aut.</sZ><sZ>35 aut.</sZ><sZ>36 aut.</sZ><sZ>37 aut.</sZ><sZ>38 aut.</sZ><sZ>39 aut.</sZ><sZ>40 aut.</sZ><sZ>41 aut.</sZ><sZ>42 aut.</sZ><sZ>43 aut.</sZ><sZ>44 aut.</sZ><sZ>45 aut.</sZ><sZ>46 aut.</sZ><sZ>47 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Booth, Timothy F" sort="Booth, Timothy F" uniqKey="Booth T" first="Timothy F." last="Booth">Timothy F. Booth</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 aut.</sZ><sZ>35 aut.</sZ><sZ>36 aut.</sZ><sZ>37 aut.</sZ><sZ>38 aut.</sZ><sZ>39 aut.</sZ><sZ>40 aut.</sZ><sZ>41 aut.</sZ><sZ>42 aut.</sZ><sZ>43 aut.</sZ><sZ>44 aut.</sZ><sZ>45 aut.</sZ><sZ>46 aut.</sZ><sZ>47 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Bowness, Donnie" sort="Bowness, Donnie" uniqKey="Bowness D" first="Donnie" last="Bowness">Donnie Bowness</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 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aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Drebot, Michael" sort="Drebot, Michael" uniqKey="Drebot M" first="Michael" last="Drebot">Michael Drebot</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 aut.</sZ><sZ>35 aut.</sZ><sZ>36 aut.</sZ><sZ>37 aut.</sZ><sZ>38 aut.</sZ><sZ>39 aut.</sZ><sZ>40 aut.</sZ><sZ>41 aut.</sZ><sZ>42 aut.</sZ><sZ>43 aut.</sZ><sZ>44 aut.</sZ><sZ>45 aut.</sZ><sZ>46 aut.</sZ><sZ>47 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Fernando, Lisa" sort="Fernando, Lisa" uniqKey="Fernando L" first="Lisa" last="Fernando">Lisa Fernando</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 aut.</sZ><sZ>35 aut.</sZ><sZ>36 aut.</sZ><sZ>37 aut.</sZ><sZ>38 aut.</sZ><sZ>39 aut.</sZ><sZ>40 aut.</sZ><sZ>41 aut.</sZ><sZ>42 aut.</sZ><sZ>43 aut.</sZ><sZ>44 aut.</sZ><sZ>45 aut.</sZ><sZ>46 aut.</sZ><sZ>47 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Flick, Ramon" sort="Flick, Ramon" uniqKey="Flick R" first="Ramon" last="Flick">Ramon Flick</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 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Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Meyers, Adrienne" sort="Meyers, Adrienne" uniqKey="Meyers A" first="Adrienne" last="Meyers">Adrienne Meyers</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 aut.</sZ><sZ>35 aut.</sZ><sZ>36 aut.</sZ><sZ>37 aut.</sZ><sZ>38 aut.</sZ><sZ>39 aut.</sZ><sZ>40 aut.</sZ><sZ>41 aut.</sZ><sZ>42 aut.</sZ><sZ>43 aut.</sZ><sZ>44 aut.</sZ><sZ>45 aut.</sZ><sZ>46 aut.</sZ><sZ>47 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Kabani, Amin" sort="Kabani, Amin" uniqKey="Kabani A" first="Amin" last="Kabani">Amin Kabani</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 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aut.</sZ><sZ>43 aut.</sZ><sZ>44 aut.</sZ><sZ>45 aut.</sZ><sZ>46 aut.</sZ><sZ>47 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Normand, Susan" sort="Normand, Susan" uniqKey="Normand S" first="Susan" last="Normand">Susan Normand</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 aut.</sZ><sZ>35 aut.</sZ><sZ>36 aut.</sZ><sZ>37 aut.</sZ><sZ>38 aut.</sZ><sZ>39 aut.</sZ><sZ>40 aut.</sZ><sZ>41 aut.</sZ><sZ>42 aut.</sZ><sZ>43 aut.</sZ><sZ>44 aut.</sZ><sZ>45 aut.</sZ><sZ>46 aut.</sZ><sZ>47 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Stroher, Ute" sort="Stroher, Ute" uniqKey="Stroher U" first="Ute" last="Stroher">Ute Stroher</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>48 aut.</sZ><sZ>49 aut.</sZ><sZ>50 aut.</sZ><sZ>51 aut.</sZ><sZ>52 aut.</sZ><sZ>53 aut.</sZ><sZ>56 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Tipples, Graham A" sort="Tipples, Graham A" uniqKey="Tipples G" first="Graham A." last="Tipples">Graham A. Tipples</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>48 aut.</sZ><sZ>49 aut.</sZ><sZ>50 aut.</sZ><sZ>51 aut.</sZ><sZ>52 aut.</sZ><sZ>53 aut.</sZ><sZ>56 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Tyler, Shaun" sort="Tyler, Shaun" uniqKey="Tyler S" first="Shaun" last="Tyler">Shaun Tyler</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>48 aut.</sZ><sZ>49 aut.</sZ><sZ>50 aut.</sZ><sZ>51 aut.</sZ><sZ>52 aut.</sZ><sZ>53 aut.</sZ><sZ>56 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Vogrig, Robert" sort="Vogrig, Robert" uniqKey="Vogrig R" first="Robert" last="Vogrig">Robert Vogrig</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>48 aut.</sZ><sZ>49 aut.</sZ><sZ>50 aut.</sZ><sZ>51 aut.</sZ><sZ>52 aut.</sZ><sZ>53 aut.</sZ><sZ>56 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Ward, Diane" sort="Ward, Diane" uniqKey="Ward D" first="Diane" last="Ward">Diane Ward</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>48 aut.</sZ><sZ>49 aut.</sZ><sZ>50 aut.</sZ><sZ>51 aut.</sZ><sZ>52 aut.</sZ><sZ>53 aut.</sZ><sZ>56 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Watson, Brynn" sort="Watson, Brynn" uniqKey="Watson B" first="Brynn" last="Watson">Brynn Watson</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>48 aut.</sZ><sZ>49 aut.</sZ><sZ>50 aut.</sZ><sZ>51 aut.</sZ><sZ>52 aut.</sZ><sZ>53 aut.</sZ><sZ>56 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Brunham, Robert C" sort="Brunham, Robert C" uniqKey="Brunham R" first="Robert C." last="Brunham">Robert C. Brunham</name><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>British Columbia Centre for Disease Control and University of British Columbia Centre for Disease Control, 655 West 12th Avenue</s1><s2>Vancouver, British Columbia V5Z 4R4</s2><s3>CAN</s3><sZ>54 aut.</sZ><sZ>55 aut.</sZ><sZ>57 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia V5Z 4R4</wicri:noRegion></affiliation></author><author><name sortKey="Krajden, Mel" sort="Krajden, Mel" uniqKey="Krajden M" first="Mel" last="Krajden">Mel Krajden</name><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>British Columbia Centre for Disease Control and University of British Columbia Centre for Disease Control, 655 West 12th Avenue</s1><s2>Vancouver, British Columbia V5Z 4R4</s2><s3>CAN</s3><sZ>54 aut.</sZ><sZ>55 aut.</sZ><sZ>57 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia V5Z 4R4</wicri:noRegion></affiliation></author><author><name sortKey="Petric, Martin" sort="Petric, Martin" uniqKey="Petric M" first="Martin" last="Petric">Martin Petric</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>48 aut.</sZ><sZ>49 aut.</sZ><sZ>50 aut.</sZ><sZ>51 aut.</sZ><sZ>52 aut.</sZ><sZ>53 aut.</sZ><sZ>56 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Skowronski, Danuta M" sort="Skowronski, Danuta M" uniqKey="Skowronski D" first="Danuta M." last="Skowronski">Danuta M. Skowronski</name><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>British Columbia Centre for Disease Control and University of British Columbia Centre for Disease Control, 655 West 12th Avenue</s1><s2>Vancouver, British Columbia V5Z 4R4</s2><s3>CAN</s3><sZ>54 aut.</sZ><sZ>55 aut.</sZ><sZ>57 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia V5Z 4R4</wicri:noRegion></affiliation></author><author><name sortKey="Upton, Chris" sort="Upton, Chris" uniqKey="Upton C" first="Chris" last="Upton">Chris Upton</name><affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Department of Biochemistry and Microbiology, University of Victoria, Post Office Box 3055 STN CSC</s1><s2>Victoria, British Columbia V8W 3P6</s2><s3>CAN</s3><sZ>58 aut.</sZ><sZ>59 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Victoria, British Columbia V8W 3P6</wicri:noRegion></affiliation></author><author><name sortKey="Roper, Rachel L" sort="Roper, Rachel L" uniqKey="Roper R" first="Rachel L." last="Roper">Rachel L. Roper</name><affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Department of Biochemistry and Microbiology, University of Victoria, Post Office Box 3055 STN CSC</s1><s2>Victoria, British Columbia V8W 3P6</s2><s3>CAN</s3><sZ>58 aut.</sZ><sZ>59 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Victoria, British Columbia V8W 3P6</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">03-0339371</idno><date when="2003">2003</date><idno type="stanalyst">PASCAL 03-0339371 INIST</idno><idno type="RBID">Pascal:03-0339371</idno><idno type="wicri:Area/PascalFrancis/Corpus">000978</idno><idno type="wicri:Area/PascalFrancis/Curation">000013</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000928</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000928</idno><idno type="wicri:doubleKey">0036-8075:2003:Marra M:the:genome:sequence</idno><idno type="wicri:Area/Main/Merge">006877</idno><idno type="wicri:Area/Main/Curation">006369</idno><idno type="wicri:Area/Main/Exploration">006369</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">The genome sequence of the SARS-associated coronavirus</title><author><name sortKey="Marra, Marco A" sort="Marra, Marco A" uniqKey="Marra M" first="Marco A." last="Marra">Marco A. Marra</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Jones, Steven J M" sort="Jones, Steven J M" uniqKey="Jones S" first="Steven J. M." last="Jones">Steven J. M. Jones</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Astell, Caroline R" sort="Astell, Caroline R" uniqKey="Astell C" first="Caroline R." last="Astell">Caroline R. Astell</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Holt, Robert A" sort="Holt, Robert A" uniqKey="Holt R" first="Robert A." last="Holt">Robert A. Holt</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Brooks Wilson, Angela" sort="Brooks Wilson, Angela" uniqKey="Brooks Wilson A" first="Angela" last="Brooks-Wilson">Angela Brooks-Wilson</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Butterfield, Yaron S N" sort="Butterfield, Yaron S N" uniqKey="Butterfield Y" first="Yaron S. N." last="Butterfield">Yaron S. N. Butterfield</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Khattra, Jaswinder" sort="Khattra, Jaswinder" uniqKey="Khattra J" first="Jaswinder" last="Khattra">Jaswinder Khattra</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Asano, Jennifer K" sort="Asano, Jennifer K" uniqKey="Asano J" first="Jennifer K." last="Asano">Jennifer K. Asano</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Barber, Sarah A" sort="Barber, Sarah A" uniqKey="Barber S" first="Sarah A." last="Barber">Sarah A. Barber</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Chan, Susanna Y" sort="Chan, Susanna Y" uniqKey="Chan S" first="Susanna Y." last="Chan">Susanna Y. Chan</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Cloutier, Alison" sort="Cloutier, Alison" uniqKey="Cloutier A" first="Alison" last="Cloutier">Alison Cloutier</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Coughlin, Shaun M" sort="Coughlin, Shaun M" uniqKey="Coughlin S" first="Shaun M." last="Coughlin">Shaun M. Coughlin</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Freeman, Doug" sort="Freeman, Doug" uniqKey="Freeman D" first="Doug" last="Freeman">Doug Freeman</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Girn, Noreen" sort="Girn, Noreen" uniqKey="Girn N" first="Noreen" last="Girn">Noreen Girn</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Griffith, Obi L" sort="Griffith, Obi L" uniqKey="Griffith O" first="Obi L." last="Griffith">Obi L. Griffith</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Leach, Stephen R" sort="Leach, Stephen R" uniqKey="Leach S" first="Stephen R." last="Leach">Stephen R. Leach</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Mayo, Michael" sort="Mayo, Michael" uniqKey="Mayo M" first="Michael" last="Mayo">Michael Mayo</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Mcdonald, Helen" sort="Mcdonald, Helen" uniqKey="Mcdonald H" first="Helen" last="Mcdonald">Helen Mcdonald</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Montgomery, Stephen B" sort="Montgomery, Stephen B" uniqKey="Montgomery S" first="Stephen B." last="Montgomery">Stephen B. Montgomery</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Pandoh, Pawan K" sort="Pandoh, Pawan K" uniqKey="Pandoh P" first="Pawan K." last="Pandoh">Pawan K. Pandoh</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Petrescu, Anca S" sort="Petrescu, Anca S" uniqKey="Petrescu A" first="Anca S." last="Petrescu">Anca S. Petrescu</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>24 aut.</sZ><sZ>25 aut.</sZ><sZ>26 aut.</sZ><sZ>27 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Robertson, A Gordon" sort="Robertson, A Gordon" uniqKey="Robertson A" first="A. Gordon" last="Robertson">A. Gordon Robertson</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>24 aut.</sZ><sZ>25 aut.</sZ><sZ>26 aut.</sZ><sZ>27 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Schein, Jacqueline E" sort="Schein, Jacqueline E" uniqKey="Schein J" first="Jacqueline E." last="Schein">Jacqueline E. Schein</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>24 aut.</sZ><sZ>25 aut.</sZ><sZ>26 aut.</sZ><sZ>27 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Siddiqui, Asim" sort="Siddiqui, Asim" uniqKey="Siddiqui A" first="Asim" last="Siddiqui">Asim Siddiqui</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>24 aut.</sZ><sZ>25 aut.</sZ><sZ>26 aut.</sZ><sZ>27 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Smailus, Duane E" sort="Smailus, Duane E" uniqKey="Smailus D" first="Duane E." last="Smailus">Duane E. Smailus</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>24 aut.</sZ><sZ>25 aut.</sZ><sZ>26 aut.</sZ><sZ>27 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Stott, Jeff M" sort="Stott, Jeff M" uniqKey="Stott J" first="Jeff M." last="Stott">Jeff M. Stott</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>24 aut.</sZ><sZ>25 aut.</sZ><sZ>26 aut.</sZ><sZ>27 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Yang, George S" sort="Yang, George S" uniqKey="Yang G" first="George S." last="Yang">George S. Yang</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>British Columbia Cancer Agency (BCCA) Genome Sciences Centre, 600 West 10th Avenue</s1><s2>Vancouver, British Columbia VSZ 4E6</s2><s3>CAN</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>24 aut.</sZ><sZ>25 aut.</sZ><sZ>26 aut.</sZ><sZ>27 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia VSZ 4E6</wicri:noRegion></affiliation></author><author><name sortKey="Plummer, Francis" sort="Plummer, Francis" uniqKey="Plummer F" first="Francis" last="Plummer">Francis Plummer</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 aut.</sZ><sZ>35 aut.</sZ><sZ>36 aut.</sZ><sZ>37 aut.</sZ><sZ>38 aut.</sZ><sZ>39 aut.</sZ><sZ>40 aut.</sZ><sZ>41 aut.</sZ><sZ>42 aut.</sZ><sZ>43 aut.</sZ><sZ>44 aut.</sZ><sZ>45 aut.</sZ><sZ>46 aut.</sZ><sZ>47 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Andonov, Anton" sort="Andonov, Anton" uniqKey="Andonov A" first="Anton" last="Andonov">Anton Andonov</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 aut.</sZ><sZ>35 aut.</sZ><sZ>36 aut.</sZ><sZ>37 aut.</sZ><sZ>38 aut.</sZ><sZ>39 aut.</sZ><sZ>40 aut.</sZ><sZ>41 aut.</sZ><sZ>42 aut.</sZ><sZ>43 aut.</sZ><sZ>44 aut.</sZ><sZ>45 aut.</sZ><sZ>46 aut.</sZ><sZ>47 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Artsob, Harvey" sort="Artsob, Harvey" uniqKey="Artsob H" first="Harvey" last="Artsob">Harvey Artsob</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 aut.</sZ><sZ>35 aut.</sZ><sZ>36 aut.</sZ><sZ>37 aut.</sZ><sZ>38 aut.</sZ><sZ>39 aut.</sZ><sZ>40 aut.</sZ><sZ>41 aut.</sZ><sZ>42 aut.</sZ><sZ>43 aut.</sZ><sZ>44 aut.</sZ><sZ>45 aut.</sZ><sZ>46 aut.</sZ><sZ>47 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Bastien, Nathalie" sort="Bastien, Nathalie" uniqKey="Bastien N" first="Nathalie" last="Bastien">Nathalie Bastien</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 aut.</sZ><sZ>35 aut.</sZ><sZ>36 aut.</sZ><sZ>37 aut.</sZ><sZ>38 aut.</sZ><sZ>39 aut.</sZ><sZ>40 aut.</sZ><sZ>41 aut.</sZ><sZ>42 aut.</sZ><sZ>43 aut.</sZ><sZ>44 aut.</sZ><sZ>45 aut.</sZ><sZ>46 aut.</sZ><sZ>47 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Bernard, Kathy" sort="Bernard, Kathy" uniqKey="Bernard K" first="Kathy" last="Bernard">Kathy Bernard</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 aut.</sZ><sZ>35 aut.</sZ><sZ>36 aut.</sZ><sZ>37 aut.</sZ><sZ>38 aut.</sZ><sZ>39 aut.</sZ><sZ>40 aut.</sZ><sZ>41 aut.</sZ><sZ>42 aut.</sZ><sZ>43 aut.</sZ><sZ>44 aut.</sZ><sZ>45 aut.</sZ><sZ>46 aut.</sZ><sZ>47 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Booth, Timothy F" sort="Booth, Timothy F" uniqKey="Booth T" first="Timothy F." last="Booth">Timothy F. Booth</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 aut.</sZ><sZ>35 aut.</sZ><sZ>36 aut.</sZ><sZ>37 aut.</sZ><sZ>38 aut.</sZ><sZ>39 aut.</sZ><sZ>40 aut.</sZ><sZ>41 aut.</sZ><sZ>42 aut.</sZ><sZ>43 aut.</sZ><sZ>44 aut.</sZ><sZ>45 aut.</sZ><sZ>46 aut.</sZ><sZ>47 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Bowness, Donnie" sort="Bowness, Donnie" uniqKey="Bowness D" first="Donnie" last="Bowness">Donnie Bowness</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 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Fernando</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 aut.</sZ><sZ>35 aut.</sZ><sZ>36 aut.</sZ><sZ>37 aut.</sZ><sZ>38 aut.</sZ><sZ>39 aut.</sZ><sZ>40 aut.</sZ><sZ>41 aut.</sZ><sZ>42 aut.</sZ><sZ>43 aut.</sZ><sZ>44 aut.</sZ><sZ>45 aut.</sZ><sZ>46 aut.</sZ><sZ>47 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Flick, Ramon" sort="Flick, Ramon" uniqKey="Flick R" first="Ramon" last="Flick">Ramon Flick</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 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aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Gray, Michael" sort="Gray, Michael" uniqKey="Gray M" first="Michael" last="Gray">Michael Gray</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 aut.</sZ><sZ>35 aut.</sZ><sZ>36 aut.</sZ><sZ>37 aut.</sZ><sZ>38 aut.</sZ><sZ>39 aut.</sZ><sZ>40 aut.</sZ><sZ>41 aut.</sZ><sZ>42 aut.</sZ><sZ>43 aut.</sZ><sZ>44 aut.</sZ><sZ>45 aut.</sZ><sZ>46 aut.</sZ><sZ>47 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Grolla, Allen" sort="Grolla, Allen" uniqKey="Grolla A" first="Allen" last="Grolla">Allen Grolla</name><affiliation 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Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Meyers, Adrienne" sort="Meyers, Adrienne" uniqKey="Meyers A" first="Adrienne" last="Meyers">Adrienne Meyers</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>28 aut.</sZ><sZ>29 aut.</sZ><sZ>30 aut.</sZ><sZ>31 aut.</sZ><sZ>32 aut.</sZ><sZ>33 aut.</sZ><sZ>34 aut.</sZ><sZ>35 aut.</sZ><sZ>36 aut.</sZ><sZ>37 aut.</sZ><sZ>38 aut.</sZ><sZ>39 aut.</sZ><sZ>40 aut.</sZ><sZ>41 aut.</sZ><sZ>42 aut.</sZ><sZ>43 aut.</sZ><sZ>44 aut.</sZ><sZ>45 aut.</sZ><sZ>46 aut.</sZ><sZ>47 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Kabani, Amin" sort="Kabani, Amin" uniqKey="Kabani A" first="Amin" last="Kabani">Amin Kabani</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Microbiology Laboratory, 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uniqKey="Stroher U" first="Ute" last="Stroher">Ute Stroher</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>48 aut.</sZ><sZ>49 aut.</sZ><sZ>50 aut.</sZ><sZ>51 aut.</sZ><sZ>52 aut.</sZ><sZ>53 aut.</sZ><sZ>56 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Tipples, Graham A" sort="Tipples, Graham A" uniqKey="Tipples G" first="Graham A." last="Tipples">Graham A. Tipples</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>48 aut.</sZ><sZ>49 aut.</sZ><sZ>50 aut.</sZ><sZ>51 aut.</sZ><sZ>52 aut.</sZ><sZ>53 aut.</sZ><sZ>56 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Tyler, Shaun" sort="Tyler, Shaun" uniqKey="Tyler S" first="Shaun" last="Tyler">Shaun Tyler</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>48 aut.</sZ><sZ>49 aut.</sZ><sZ>50 aut.</sZ><sZ>51 aut.</sZ><sZ>52 aut.</sZ><sZ>53 aut.</sZ><sZ>56 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Vogrig, Robert" sort="Vogrig, Robert" uniqKey="Vogrig R" first="Robert" last="Vogrig">Robert Vogrig</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>48 aut.</sZ><sZ>49 aut.</sZ><sZ>50 aut.</sZ><sZ>51 aut.</sZ><sZ>52 aut.</sZ><sZ>53 aut.</sZ><sZ>56 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Ward, Diane" sort="Ward, Diane" uniqKey="Ward D" first="Diane" last="Ward">Diane Ward</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>48 aut.</sZ><sZ>49 aut.</sZ><sZ>50 aut.</sZ><sZ>51 aut.</sZ><sZ>52 aut.</sZ><sZ>53 aut.</sZ><sZ>56 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Watson, Brynn" sort="Watson, Brynn" uniqKey="Watson B" first="Brynn" last="Watson">Brynn Watson</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>48 aut.</sZ><sZ>49 aut.</sZ><sZ>50 aut.</sZ><sZ>51 aut.</sZ><sZ>52 aut.</sZ><sZ>53 aut.</sZ><sZ>56 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Brunham, Robert C" sort="Brunham, Robert C" uniqKey="Brunham R" first="Robert C." last="Brunham">Robert C. Brunham</name><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>British Columbia Centre for Disease Control and University of British Columbia Centre for Disease Control, 655 West 12th Avenue</s1><s2>Vancouver, British Columbia V5Z 4R4</s2><s3>CAN</s3><sZ>54 aut.</sZ><sZ>55 aut.</sZ><sZ>57 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia V5Z 4R4</wicri:noRegion></affiliation></author><author><name sortKey="Krajden, Mel" sort="Krajden, Mel" uniqKey="Krajden M" first="Mel" last="Krajden">Mel Krajden</name><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>British Columbia Centre for Disease Control and University of British Columbia Centre for Disease Control, 655 West 12th Avenue</s1><s2>Vancouver, British Columbia V5Z 4R4</s2><s3>CAN</s3><sZ>54 aut.</sZ><sZ>55 aut.</sZ><sZ>57 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia V5Z 4R4</wicri:noRegion></affiliation></author><author><name sortKey="Petric, Martin" sort="Petric, Martin" uniqKey="Petric M" first="Martin" last="Petric">Martin Petric</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>National Microbiology Laboratory, 1015 Arlington Street</s1><s2>Winnipeg, Manitoba R3E 3R2</s2><s3>CAN</s3><sZ>48 aut.</sZ><sZ>49 aut.</sZ><sZ>50 aut.</sZ><sZ>51 aut.</sZ><sZ>52 aut.</sZ><sZ>53 aut.</sZ><sZ>56 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, Manitoba R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Skowronski, Danuta M" sort="Skowronski, Danuta M" uniqKey="Skowronski D" first="Danuta M." last="Skowronski">Danuta M. Skowronski</name><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>British Columbia Centre for Disease Control and University of British Columbia Centre for Disease Control, 655 West 12th Avenue</s1><s2>Vancouver, British Columbia V5Z 4R4</s2><s3>CAN</s3><sZ>54 aut.</sZ><sZ>55 aut.</sZ><sZ>57 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, British Columbia V5Z 4R4</wicri:noRegion></affiliation></author><author><name sortKey="Upton, Chris" sort="Upton, Chris" uniqKey="Upton C" first="Chris" last="Upton">Chris Upton</name><affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Department of Biochemistry and Microbiology, University of Victoria, Post Office Box 3055 STN CSC</s1><s2>Victoria, British Columbia V8W 3P6</s2><s3>CAN</s3><sZ>58 aut.</sZ><sZ>59 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Victoria, British Columbia V8W 3P6</wicri:noRegion></affiliation></author><author><name sortKey="Roper, Rachel L" sort="Roper, Rachel L" uniqKey="Roper R" first="Rachel L." last="Roper">Rachel L. Roper</name><affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Department of Biochemistry and Microbiology, University of Victoria, Post Office Box 3055 STN CSC</s1><s2>Victoria, British Columbia V8W 3P6</s2><s3>CAN</s3><sZ>58 aut.</sZ><sZ>59 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Victoria, British Columbia V8W 3P6</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Science : (Washington, D.C.)</title><title level="j" type="abbreviated">Science : (Wash. D.C.)</title><idno type="ISSN">0036-8075</idno><imprint><date when="2003">2003</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Science : (Washington, D.C.)</title><title level="j" type="abbreviated">Science : (Wash. D.C.)</title><idno type="ISSN">0036-8075</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Coronavirus</term><term>Genetic distance</term><term>Genome</term><term>Nucleotide sequence</term><term>Phylogeny</term><term>Severe acute respiratory syndrome</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Coronavirus</term><term>Génome</term><term>Séquence nucléotide</term><term>Phylogenèse</term><term>Distance génétique</term><term>Syndrome respiratoire aigu sévère</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We sequenced the 29,751-base genome of the severe acute respiratory syndrome (SARS)-associated coronavirus known as the Tor2 isolate. The genome sequence reveals that this coronavirus is only moderately related to other known coronaviruses, including two human coronaviruses, HCoV-OC43 and HCoV-229E. Phylogenetic analysis of the predicted viral proteins indicates that the virus does not closely resemble any of the three previously known groups of coronaviruses. The genome sequence will aid in the diagnosis of SARS virus infection in humans and potential animal hosts (using polymerase chain reaction and immunological tests), in the development of antivirals (including neutralizing antibodies), and in the identification of putative epitopes for vaccine development.</div></front></TEI><affiliations><list><country><li>Canada</li></country></list><tree><country name="Canada"><noRegion><name sortKey="Marra, Marco A" sort="Marra, Marco A" uniqKey="Marra M" first="Marco A." last="Marra">Marco A. Marra</name></noRegion><name sortKey="Andonov, Anton" sort="Andonov, Anton" uniqKey="Andonov A" first="Anton" last="Andonov">Anton Andonov</name><name sortKey="Artsob, Harvey" sort="Artsob, Harvey" uniqKey="Artsob H" first="Harvey" last="Artsob">Harvey Artsob</name><name sortKey="Asano, Jennifer K" sort="Asano, Jennifer K" uniqKey="Asano J" first="Jennifer K." last="Asano">Jennifer K. Asano</name><name sortKey="Astell, Caroline R" sort="Astell, Caroline R" uniqKey="Astell C" first="Caroline R." last="Astell">Caroline R. Astell</name><name sortKey="Barber, Sarah A" sort="Barber, Sarah A" uniqKey="Barber S" first="Sarah A." last="Barber">Sarah A. Barber</name><name sortKey="Bastien, Nathalie" sort="Bastien, Nathalie" uniqKey="Bastien N" first="Nathalie" last="Bastien">Nathalie Bastien</name><name sortKey="Bernard, Kathy" sort="Bernard, Kathy" uniqKey="Bernard K" first="Kathy" last="Bernard">Kathy Bernard</name><name sortKey="Booth, Timothy F" sort="Booth, Timothy F" uniqKey="Booth T" first="Timothy F." last="Booth">Timothy F. Booth</name><name sortKey="Bowness, Donnie" sort="Bowness, Donnie" uniqKey="Bowness D" first="Donnie" last="Bowness">Donnie Bowness</name><name sortKey="Brooks Wilson, Angela" sort="Brooks Wilson, Angela" uniqKey="Brooks Wilson A" first="Angela" last="Brooks-Wilson">Angela Brooks-Wilson</name><name sortKey="Brunham, Robert C" sort="Brunham, Robert C" uniqKey="Brunham R" first="Robert C." last="Brunham">Robert C. Brunham</name><name sortKey="Butterfield, Yaron S N" sort="Butterfield, Yaron S N" uniqKey="Butterfield Y" first="Yaron S. N." last="Butterfield">Yaron S. N. Butterfield</name><name sortKey="Chan, Susanna Y" sort="Chan, Susanna Y" uniqKey="Chan S" first="Susanna Y." last="Chan">Susanna Y. Chan</name><name sortKey="Cloutier, Alison" sort="Cloutier, Alison" uniqKey="Cloutier A" first="Alison" last="Cloutier">Alison Cloutier</name><name sortKey="Coughlin, Shaun M" sort="Coughlin, Shaun M" uniqKey="Coughlin S" first="Shaun M." last="Coughlin">Shaun M. Coughlin</name><name sortKey="Czub, Martin" sort="Czub, Martin" uniqKey="Czub M" first="Martin" last="Czub">Martin Czub</name><name sortKey="Drebot, Michael" sort="Drebot, Michael" uniqKey="Drebot M" first="Michael" last="Drebot">Michael Drebot</name><name sortKey="Feldmann, Heinz" sort="Feldmann, Heinz" uniqKey="Feldmann H" first="Heinz" last="Feldmann">Heinz Feldmann</name><name sortKey="Fernando, Lisa" sort="Fernando, Lisa" uniqKey="Fernando L" first="Lisa" last="Fernando">Lisa Fernando</name><name sortKey="Flick, Ramon" sort="Flick, Ramon" uniqKey="Flick R" first="Ramon" last="Flick">Ramon Flick</name><name sortKey="Freeman, Doug" sort="Freeman, Doug" uniqKey="Freeman D" first="Doug" last="Freeman">Doug Freeman</name><name sortKey="Garbutt, Michael" sort="Garbutt, Michael" uniqKey="Garbutt M" first="Michael" last="Garbutt">Michael Garbutt</name><name sortKey="Girn, Noreen" sort="Girn, Noreen" uniqKey="Girn N" first="Noreen" last="Girn">Noreen Girn</name><name sortKey="Gray, Michael" sort="Gray, Michael" uniqKey="Gray M" first="Michael" last="Gray">Michael Gray</name><name sortKey="Griffith, Obi L" sort="Griffith, Obi L" uniqKey="Griffith O" first="Obi L." last="Griffith">Obi L. Griffith</name><name sortKey="Grolla, Allen" sort="Grolla, Allen" uniqKey="Grolla A" first="Allen" last="Grolla">Allen Grolla</name><name sortKey="Holt, Robert A" sort="Holt, Robert A" uniqKey="Holt R" first="Robert A." last="Holt">Robert A. Holt</name><name sortKey="Jones, Steven" sort="Jones, Steven" uniqKey="Jones S" first="Steven" last="Jones">Steven Jones</name><name sortKey="Jones, Steven J M" sort="Jones, Steven J M" uniqKey="Jones S" first="Steven J. M." last="Jones">Steven J. M. Jones</name><name sortKey="Kabani, Amin" sort="Kabani, Amin" uniqKey="Kabani A" first="Amin" last="Kabani">Amin Kabani</name><name sortKey="Khattra, Jaswinder" sort="Khattra, Jaswinder" uniqKey="Khattra J" first="Jaswinder" last="Khattra">Jaswinder Khattra</name><name sortKey="Krajden, Mel" sort="Krajden, Mel" uniqKey="Krajden M" first="Mel" last="Krajden">Mel Krajden</name><name sortKey="Leach, Stephen R" sort="Leach, Stephen R" uniqKey="Leach S" first="Stephen R." last="Leach">Stephen R. Leach</name><name sortKey="Mayo, Michael" sort="Mayo, Michael" uniqKey="Mayo M" first="Michael" last="Mayo">Michael Mayo</name><name sortKey="Mcdonald, Helen" sort="Mcdonald, Helen" uniqKey="Mcdonald H" first="Helen" last="Mcdonald">Helen Mcdonald</name><name sortKey="Meyers, Adrienne" sort="Meyers, Adrienne" uniqKey="Meyers A" first="Adrienne" last="Meyers">Adrienne Meyers</name><name sortKey="Montgomery, Stephen B" sort="Montgomery, Stephen B" uniqKey="Montgomery S" first="Stephen B." last="Montgomery">Stephen B. Montgomery</name><name sortKey="Normand, Susan" sort="Normand, Susan" uniqKey="Normand S" first="Susan" last="Normand">Susan Normand</name><name sortKey="Pandoh, Pawan K" sort="Pandoh, Pawan K" uniqKey="Pandoh P" first="Pawan K." last="Pandoh">Pawan K. Pandoh</name><name sortKey="Petrescu, Anca S" sort="Petrescu, Anca S" uniqKey="Petrescu A" first="Anca S." last="Petrescu">Anca S. Petrescu</name><name sortKey="Petric, Martin" sort="Petric, Martin" uniqKey="Petric M" first="Martin" last="Petric">Martin Petric</name><name sortKey="Plummer, Francis" sort="Plummer, Francis" uniqKey="Plummer F" first="Francis" last="Plummer">Francis Plummer</name><name sortKey="Robertson, A Gordon" sort="Robertson, A Gordon" uniqKey="Robertson A" first="A. Gordon" last="Robertson">A. Gordon Robertson</name><name sortKey="Roper, Rachel L" sort="Roper, Rachel L" uniqKey="Roper R" first="Rachel L." last="Roper">Rachel L. Roper</name><name sortKey="Schein, Jacqueline E" sort="Schein, Jacqueline E" uniqKey="Schein J" first="Jacqueline E." last="Schein">Jacqueline E. Schein</name><name sortKey="Siddiqui, Asim" sort="Siddiqui, Asim" uniqKey="Siddiqui A" first="Asim" last="Siddiqui">Asim Siddiqui</name><name sortKey="Skowronski, Danuta M" sort="Skowronski, Danuta M" uniqKey="Skowronski D" first="Danuta M." last="Skowronski">Danuta M. Skowronski</name><name sortKey="Smailus, Duane E" sort="Smailus, Duane E" uniqKey="Smailus D" first="Duane E." last="Smailus">Duane E. Smailus</name><name sortKey="Stott, Jeff M" sort="Stott, Jeff M" uniqKey="Stott J" first="Jeff M." last="Stott">Jeff M. Stott</name><name sortKey="Stroher, Ute" sort="Stroher, Ute" uniqKey="Stroher U" first="Ute" last="Stroher">Ute Stroher</name><name sortKey="Tipples, Graham A" sort="Tipples, Graham A" uniqKey="Tipples G" first="Graham A." last="Tipples">Graham A. Tipples</name><name sortKey="Tyler, Shaun" sort="Tyler, Shaun" uniqKey="Tyler S" first="Shaun" last="Tyler">Shaun Tyler</name><name sortKey="Upton, Chris" sort="Upton, Chris" uniqKey="Upton C" first="Chris" last="Upton">Chris Upton</name><name sortKey="Vogrig, Robert" sort="Vogrig, Robert" uniqKey="Vogrig R" first="Robert" last="Vogrig">Robert Vogrig</name><name sortKey="Ward, Diane" sort="Ward, Diane" uniqKey="Ward D" first="Diane" last="Ward">Diane Ward</name><name sortKey="Watson, Brynn" sort="Watson, Brynn" uniqKey="Watson B" first="Brynn" last="Watson">Brynn Watson</name><name sortKey="Yan Li" sort="Yan Li" uniqKey="Yan Li" last="Yan Li">YAN LI</name><name sortKey="Yang, George S" sort="Yang, George S" uniqKey="Yang G" first="George S." last="Yang">George S. Yang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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